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BioEffective A


Bioeffective® A

Conifer Green Needle Complex (CGNC) is a biologically active substance derived from green conifer needles. It contains Chlorophyll derivatives, carotenoids, Vitamin E and K, phytosterols, polyphenols, squalene, minerals and essential oils.

Chlorophyll derivatives are known to have antioxidant and anti-microbial activity. They stimulate a positive immune response and can help with wounds, burns and ulcers. (Moiseyeva M.V., Mikhailesc G.A., 2000). They also have anti-mutagenic, anticarcinogenic and anti-inflammatory properties (Chernomrsky S. et al, 2003)

Carotenoids have antioxidant and immune modulating activity. Epidemiological and experimental studies have confirmed the ability of carotenoids to prevent the development of tumours, atherosclerosis and cardiovascular diseases (Tapiero H et al, 2004)

Vitamin E is an important antioxidant in the body. Apart from being involved in cellular division and tissue respiration it is important for maintaining stability in cellular membranes. Epidemiological and experimental studies showed a protective response from Vitamin E in disorders like atherosclerosis, certain types of cancer, diabetes, chronic inflammation, cataracts and Alzheimer’s Disease (Brigelius-Flohe R et al., 2002; Dutta A, Dutta SK., 2003)

Vitamin K helps regulate calcium formation and resorption; regulates blood coagulation and increases the resistance of vessel walls to damage (Vermeer C t al., 2004)

Phytosterols are antioxidant and anticarcinogenic. Epidemiological studies have proven that taking phytosterols with food reduces the risk of ischemic heart disease by 20-25% (Gylling H., Miettinen TA., 2005). Phytosterols also inhibit the absorption of cholesterol, and reduce cholesterol and lipids in the blood (de Jong JH et al., 2003). Epidemiological studies showed that increased intake of phytosterols was associated with a reduction in risk of cancer of the large intestine, prostate & mammary glands (Awad AB., Fink CS 2000) and lungs (Mendilaharsu M et al., 1998)

Polyprenols stimulate the immune system, and have antistress, anti-ulcerogenic and wound healing activity (Roschin V.I., 2000).

Squalene is an antioxidant and helps reduce cholesterol and is anticarcinogenic (Kelly GS., 1999). Studies on rodents showed that squalene inhibited cancer causing process in the large intestines, lungs and skin. The mechanism for this was attributed to its antioxidant activity (Smith TJ., 2000).

CGNC is a powerful antioxidant and has been trialled against Vitamin E alone and Lipoic acid and has been shown to be more effective as an antioxidant.

Why Do We Need Anti-oxidants?

Free radicals are formed during biochemical and cellular functions in the body. Free radical formation and their toxic effect on cell function is called oxidative stress. The production of free radicals should normally be balanced by an intake of antioxidant-rich foods. Unfortunately, with preserved, frozen, canned and processed foods, as well as soils being deplete in a range of minerals like selenium, the population today is not taking in as much antioxidants from their foods as they think.

What is Oxidative Stress?

The stress that free radicals have on the body is called oxidative stress. It stems from the imbalance between the formation and neutralisation of these free radicals or pro-oxidants.

Free radicals are highly reactive, reacting with cellular DNA, proteins, lipids and other components. These oxidative stress reactions can lead to DNA damage, cellular malfunction causing a decrease of the energy in the cells, as well as cell membrane damage.

Oxidative stress is involved with:

  • Atherosclerosis
  • Parkinson’s Disease
  • Heart Disease
  • Alzheimer’s Disease
  • Chronic Fatigue Syndrome
  • Premature Aging
  • Cancer
  • And many other disorders

External factors such as pollution and smoking can also trigger the production of free radicals. Our biggest pollutant can be our day-to-day stress which could involve emotional, psychological or even financial stressors.

To counteract oxidative stress, the body produces an armoury of antioxidants to defend itself. It is the job of antioxidants to neutralise or 'mop up' free radicals that can harm our cells.

The body's ability to produce antioxidants (its metabolic process) is controlled by a person’s genetic makeup and influenced by their exposure to environmental factors such as diet and smoking.

Changes in our lifestyles, which include more environmental pollution, less quality in our diets and greater stress levels, mean that we are exposed to more free radicals than ever before.

Will eating antioxidants protect you from disease?

Studies have shown that people who eat a diet that is rich in fruit and vegetables are less likely to get diseases such as cancer, heart disease and stroke.

It has not yet been proven that antioxidants alone are responsible for this drop in risk.

For example, the research that has been done on the effect of diet on cancer has been difficult to conduct and interpret.

Even so, there is now a good body of evidence to indicate the protective effect of fruit and vegetables on many common cancers, including those of colon, breast and bladder.

Foods like tomatoes, citrus, carrots, green leafy vegetables and drinking green tea can provide you with some antioxidants. But is the amount you are eating enough to counter your body’s oxidative stress and prevent disease? And will it be enough if your body succumbs to a disorder? Sometimes, supplementing with a strong antioxidant is a faster way to heal the body or a more efficient preventative.

Clinical and Pharmacological Trials of CGNC:

Conifer Green Needle Complex has been studied in Russia for its clinical effects in a range of illnesses including:

  • Acute respiratory infections
  • Periodontal disease
  • Detoxification and heavy metal elimination
  • Anti-carcinogenic activity in rodents
  • Cholesterol and heart health
  • Gastrointestinal health eg Gastritis and dyspepsia (heartburn)


To find out whether your condition could be helped by Bioeffective® A please ring for an appointment.


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